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Important Safety Information (ISI)

SUBOXONE® (buprenorphine HCl/naloxone HCl dihydrate sublingual tablets) (CIII) is indicated for the treatment of opioid dependence.

It is extremely dangerous to take benzodiazepines or other depressants while taking SUBOXONE. A serious overdose and death may occur if benzodiazepines, sedatives, tranquilizers, antidepressants, or alcohol are taken at the same time as SUBOXONE.

SUBOXONE has potential for abuse and produces dependence of the opioid type, with a milder withdrawal syndrome than full agonists.

Cytolytic hepatitis and hepatitis with jaundice have been observed in the addicted population receiving buprenorphine.

Allergic reactions including bronchospasm, angioneurotic edema, and anaphylactic shock have been reported in patients taking buprenorphine.

There are no adequate and well-controlled studies of SUBOXONE (a Category C medication) in pregnancy.

Caution should be exercised when driving cars or operating machinery.

Always store buprenorphine-containing medications safely and out of the reach and sight of children. Destroy any unused medication appropriately.

The most commonly reported adverse events with SUBOXONE include: headache (36%, placebo 22%), withdrawal syndrome (25%, placebo 37%), pain (22%, placebo 19%), insomnia (14%, placebo 16%), nausea (15%, placebo 11%), and constipation (12%, placebo 3%). Please see full Prescribing Information for a complete list.

To report an adverse event caused by taking SUBOXONE, please call 1-877-782-6966. You are also encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see full US Prescribing Information for SUBOXONE.

I have read and understood the Important Safety Information.

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Experiences & success stories

You’re not alone

Sharing stories can help you—and can help others. In fact, making sense of your experience can and should be an everyday thing. Journaling, tracking, and being part of a community can help you put your experiences in context and move your life in a positive direction.

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Meet the Care Coaches: Jess & Sandi
Two Here to Help® Care Coaches talk about what they offer program participants—and why they love the work they do.

Jessica & Treatment
When Jessica tried to quit opioids cold turkey, she couldn't stop thinking about misuse. See how treatment with SUBOXONE—including counseling and support from Here to Help®—helped make it possible for Jessica to plan for the future again.

Jessica & Dr Rodgers
Could the Here to Help® Program strengthen your commitment to treatment? Jessica and Dr Rodgers discuss how Here to Help has made their office visits more productive.

Jess & Jessica: Care Coaching
See how Jessica's partnership with her Here to Help® Care Coach has helped her understand her dependence better—and take positive steps.

Mark: Treatment & Here to Help
Mark was prescribed opioids for pain, but ended up with a destructive dependency. It's been a long journey, but SUBOXONE, counseling, and Here to Help® helped Mark get his life back.

Jessica's Story
Jessica's misuse of opioids started in high school and soon spun out of control. Today—married and a stay-at-home mom—Jessica combines SUBOXONE® (buprenorphine HCl/naloxone HCl dihydrate sublingual tablets) (CIII), counseling, and Here to Help® to keep herself on track.

Jenn's Story
Jennifers opioid use began as treatment for pain...her dependence led her to feelings of shame and detachment. Today, with continuing treatment, she works in the medical field and plans to get married.

John's Story
John's recreational use of opioids derailed his college education and his future. Thanks to his commitment, he's back on track at age 24.

Greg's Story
Greg's opioid use for surgical pain grew into dependence that almost cost him his family. Today he's enjoying all the things he values.

LeeAnn and Greg's Story
LeeAnn and Greg felt the strain of opioid dependence on their 14-year marriage. Now LeeAnn is Greg's most supportive caregiver.

Ellis's Story
In his 50s now, Ellis spent most of his adult life dependent on opioids, but never stopped trying to beat his addiction.

Dave's Story
Dave has struggled with addiction since his teens, sometimes getting and staying clean for years, and then slipping back.

Learn from others who've been there too

Hear from patients who have been treated for opioid dependence as they share, in their own words, how treatment that includes SUBOXONE has allowed them to manage their disease and focus on other aspects of their lives. Their personal feelings and situations don't necessarily reflect the experiences of every patient treated with SUBOXONE.

SUBOXONE (buprenorphine HCl/naloxone HCl dihydrate) CIII sublingual tablets
It was just nonstop with pain medication...I hadn't realized my using made me so isolated.

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This site is sponsored by Reckitt Benckiser Pharmaceuticals Inc. and intended for residents of the United States.
SUBOXONE® and Here to Help® are registered trademarks of Reckitt Benckiser Healthcare (UK) Ltd.
This site is provided for educational and informational purposes only and is not intended
as a substitute for direct consultation with a qualified mental health professional.
Patient quotes are hypothetical.
© 2009 Reckitt Benckiser Pharmaceuticals Inc.

Important Safety Information (ISI)

SUBOXONE® (buprenorphine HCl/naloxone HCl dihydrate sublingual tablets) (CIII) is indicated for the treatment of opioid dependence.

It is extremely dangerous to take benzodiazepines or other depressants while taking SUBOXONE. A serious overdose and death may occur if benzodiazepines, sedatives, tranquilizers, antidepressants, or alcohol are taken at the same time as SUBOXONE.

SUBOXONE has potential for abuse and produces dependence of the opioid type, with a milder withdrawal syndrome than full agonists.

Cytolytic hepatitis and hepatitis with jaundice have been observed in the addicted population receiving buprenorphine.

Allergic reactions including bronchospasm, angioneurotic edema, and anaphylactic shock have been reported in patients taking buprenorphine.

There are no adequate and well-controlled studies of SUBOXONE (a Category C medication) in pregnancy.

Caution should be exercised when driving cars or operating machinery.

Always store buprenorphine-containing medications safely and out of the reach and sight of children. Destroy any unused medication appropriately.

The most commonly reported adverse events with SUBOXONE include: headache (36%, placebo 22%), withdrawal syndrome (25%, placebo 37%), pain (22%, placebo 19%), insomnia (14%, placebo 16%), nausea (15%, placebo 11%), and constipation (12%, placebo 3%). Please see full Prescribing Information for a complete list.

To report an adverse event caused by taking SUBOXONE, please call 1-877-782-6966. You are also encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see full US Prescribing Information for SUBOXONE.